Science and Technology Indonesia (Jan 2022)

The Film of Chitosan-ZnO Nanoparticles-CTAB : Synthesis, Characterization and In Vitro Study

  • Ahmad Fatoni,
  • Herlina Silvia Yessica,
  • Aldilah,
  • Mia Almi,
  • Agnes Rendowaty,
  • Romsiah,
  • Lasmaryna Sirumapea,
  • Nurlisa Hidayati

DOI
https://doi.org/10.26554/sti.2022.7.1.58-66
Journal volume & issue
Vol. 7, no. 1
pp. 58 – 66

Abstract

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The synthesis of film chitosan- ZnO nanoparticles-CTAB were studied. The aims of this research were synthesis of the film chitosan-ZnO nanoparticles-CTAB, its characterization and, application of the film chitosan-ZnO nanoparticles-CTAB as an antibacterial of Staphylococcus aureus. The film of chitosan-ZnO nanoparticles-CTAB was synthesized by the casting method and characterized by FTIR spectroscopy and X-ray diffraction, respectively. The film of chitosan-ZnO nanoparticles-CTAB was used as an antibacterial agent with the agar disk diffusion method. The result showed that the Zn-O group at the film of chitosan-ZnO nanoparticles-CTAB was detected at a wavenumber between 578-619 cm-1. The band at 2852.72-2854.65 cm-1 is the band of C-H groups in the film of chitosan-ZnO nanoparticles-CTAB. The effect of ZnO nanoparticles-CTAB changed of the physical structure of chitosan. The average of the inhibition zone in the film of chitosan-ZnO nanoparticles-CTAB I, II and III was 10.37 ± 0.55, 11.31± 1.27 and 10.38 ± 0.24 mm respectively.

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