Monaldi Archives for Chest Disease (Aug 2020)

ROS1 positive non-small cell lung cancer with pulmonary embolism in a 22-year woman

  • Ananda Datta,
  • Satya Padmaja Mantha,
  • Suvradeep Mitra,
  • Prasanta Mohapatra,
  • M Srikanth Goud,
  • Manoj Kumar Panigrahi

DOI
https://doi.org/10.4081/monaldi.2020.1435
Journal volume & issue
Vol. 90, no. 3

Abstract

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ROS1-rearrangement occurs in 1-2% of non-small cell lung cancer (NSCLC). This mutation is predominantly seen in relatively young, non-smoker, female with adenocarcinoma. Association of pulmonary embolism with ROS1-rearranged NSCLC has been suggested. We report a case of a 22-year-old woman with ROS1-positive NSCLC and pulmonary embolism. This case possibly represents the youngest patient in the literature.

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