Design, Synthesis, Molecular Docking and Antibacterial Screening of Some Quinolone Compounds

Affiliations

Lucia Pintilie: National Institute for Chemical, Pharmaceutical Research and Development (ICCF), Bucharest, 112 Vitan Av., 031299 Bucharest, Romania
Constantin Tanase: National Institute for Chemical, Pharmaceutical Research and Development (ICCF), Bucharest, 112 Vitan Av., 031299 Bucharest, Romania
Elena Mihai: National Institute for Chemical, Pharmaceutical Research and Development (ICCF), Bucharest, 112 Vitan Av., 031299 Bucharest, Romania
Maria Maganu: Organic Chemistry Center “C.D.Nenitescu”, 202 B Splaiul Independentei, 060023 Bucharest 6, Romania
Miron Teodor Caproiu: Organic Chemistry Center “C.D.Nenitescu”, 202 B Splaiul Independentei, 060023 Bucharest 6, Romania

Abstract

Drugs belonging to the quinolone compounds are characterized by a quicker biological activity and a broad antibacterial spectrum [1−4]. [...]