Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis

Dong Qianlan; Wang Qiong; Yan Xiaohui; Wang Xiaoming; Li Zhenjiang; Zhang Linping

doi:10.1515/med-2021-0328

Open Medicine (Sep 2021)

Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis

Dong Qianlan,
Wang Qiong,
Yan Xiaohui,
Wang Xiaoming,
Li Zhenjiang,
Zhang Linping

Affiliations

Dong Qianlan: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China
Wang Qiong: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China
Yan Xiaohui: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China
Wang Xiaoming: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China
Li Zhenjiang: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China
Zhang Linping: Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, China

DOI: https://doi.org/10.1515/med-2021-0328
Journal volume & issue: Vol. 16, no. 1
pp. 1336 – 1349

Abstract

Read online

Diabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN.

Published in Open Medicine

ISSN: 2391-5463 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine
Website: https://www.degruyter.com/journal/key/med/html

About the journal

Abstract

Keywords