Association of IFNA16 and TNFRSF19 Polymorphisms with Intramuscular Fat Content and Fatty Acid Composition in Pigs

Supamit Mekchay; Nanthana Pothakam; Worrarak Norseeda; Pantaporn Supakankul; Tawatchai Teltathum; Guisheng Liu; Watcharapong Naraballobh; Trisadee Khamlor; Korawan Sringarm; Patcharin Krutmuang

doi:10.3390/biology11010109

Biology (Jan 2022)

Association of IFNA16 and TNFRSF19 Polymorphisms with Intramuscular Fat Content and Fatty Acid Composition in Pigs

Supamit Mekchay,
Nanthana Pothakam,
Worrarak Norseeda,
Pantaporn Supakankul,
Tawatchai Teltathum,
Guisheng Liu,
Watcharapong Naraballobh,
Trisadee Khamlor,
Korawan Sringarm,
Patcharin Krutmuang

Affiliations

Supamit Mekchay: Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Nanthana Pothakam: Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Worrarak Norseeda: Department of Agriculture, Faculty of Agricultural Technology, Lampang Rajabhat University, Lampang 52100, Thailand
Pantaporn Supakankul: Division of Animal Science, School of Agriculture and Natural Resources, University of Phayao, Phayao 56000, Thailand
Tawatchai Teltathum: Mae Hong Son Livestock Research and Breeding Center, Mae Hong Son 58000, Thailand
Guisheng Liu: Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430064, China
Watcharapong Naraballobh: Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Trisadee Khamlor: Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Korawan Sringarm: Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Patcharin Krutmuang: Innovative Agriculture Research Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand

DOI: https://doi.org/10.3390/biology11010109
Journal volume & issue: Vol. 11, no. 1
p. 109

Abstract

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Interferon-alpha-16 (IFNA16) and tumor necrosis factor receptor superfamily member 19 (TNFRSF19) are cytokines that may play a role in adipogenesis and fatness. Single nucleotide polymorphisms (SNPs) of the porcine IFNA16 and TNFRSF19 genes were verified and their association with intramuscular fat (IMF) content and fatty acid (FA) composition were evaluated in commercial crossbred pigs. Two non-synonymous SNPs of the porcine IFNA16 c.413G > A and TNFRSF19 c.860G > C loci were detected in commercial crossbred pigs. The porcine IFNA16 c.413G >A polymorphism was significantly associated with stearic acid, total saturated FAs (SFAs), and the ratio of monounsaturated FAs (MUFAs) to SFAs (p TNFRSF19 c.860G > C polymorphism was found to be significantly associated with IMF content and arachidic acid levels (p IFNA16 and TNFRSF19 polymorphisms are related to IMF content and/or FA composition and affirmed the importance of these cytokine genes as potential candidate genes for lipid deposition and FA composition in the muscle tissue of pigs.

Published in Biology

ISSN: 2079-7737 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: https://www.mdpi.com/journal/biology

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