Chinese Medical Journal (Jan 2017)

Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013

  • Ying Peng,
  • Song-Hua Chen,
  • Le Zhang,
  • Bin Chen,
  • Ming-Wu Zhang,
  • Tie-Niu He,
  • Fei Wang,
  • Cheng-Liang Chai,
  • Lin Zhou,
  • Yu Zhang,
  • Xiao-Meng Wang,
  • Zhongwei Jia

DOI
https://doi.org/10.4103/0366-6999.213413
Journal volume & issue
Vol. 130, no. 17
pp. 2021 – 2026

Abstract

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Background: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. Methods: We conducted a study in Zhejiang Province during 2009–2013 to screen for MDR-TB patients among the low MDR-TB risk patients and five subpopulations of high MDR-TB risk patients. The number, prevalence, and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB. Results: A total of 200 and 791 MDR-TB cases were, respectively, identified from the 9830 new TB cases and 2372 high-risk suspects who took MDR-TB screening from 2009 to 2013. The MDR-TB rates went down in both of the new TB patients and five MDR-TB high-risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.3% in 2011 to 27.0% in 2012 to 26.0% in 2013. Conclusions: The study indicated that MDR-TB burden among new TB patients was high, thus screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide.

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