Journal of Investigative Medicine High Impact Case Reports (Apr 2023)

Catastrophic Antiphospholipid Syndrome as a Complication of COVID-19 Infection

  • Lauren Bitterman MD,
  • Mahdis Solhjoo MD,
  • Vivek Shah MD,
  • Sue Min Kwon MD,
  • Karina Torralba MD,
  • Hana Kazbour MD

DOI
https://doi.org/10.1177/23247096231165736
Journal volume & issue
Vol. 11

Abstract

Read online

COVID-19 infection has been found to precipitate hypercoagulability and transiently increase antiphospholipid antibodies. However, it is yet to be determined how likely these transient changes contribute to thrombotic events and antiphospholipid syndrome. We present a case in which antiphospholipid antibodies were detected in the presence of significant thromboses. The patient was subsequently treated for suspected catastrophic antiphospholipid syndrome following COVID-19 infection.