Journal of Stress Physiology & Biochemistry (May 2009)

ENZYMES OF ENERGY METABOLISM IN BRAIN AND CHRONIC STRESS

  • Koshoridze N.I.,
  • Menabde K.O.,
  • Chachua M.V.,
  • Kuchukashvili Z.T.,
  • Chipashvili M.D.

Journal volume & issue
Vol. 5, no. 1-2
pp. 32 – 37

Abstract

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The development of changes in the activity of creatinkinase, aldolase and succinatdehydrogenase in brain cells under 30-day long stress induced by isolation and violated diurnal cycle has been studied. It was shown that these enzymes heterogeneously responded to 30-day long stress. Particular sensitivity was recorded in the case of succinatedehydrogenase, which showed the decline of activityin various sections of the brain by 60-80% on average. Unlike succinatedehydrogenase, aldolase activity increased on the 10th day of stress and then declined. Similar results were observed in relationto phosphokinase activity.

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