Brazilian Archives of Biology and Technology (Jun 2024)

Emulgels Containing Propolis and Curcumin for the Treatment of Mastitis and Umbilical Cord Healing

  • Rafaela Said dos Santos,
  • Katieli da Silva Souza Campanholi,
  • Amanda Sandes Bispo,
  • Wilker Caetano,
  • Magali Soares dos Santos Pozza,
  • Henrique Leal Perez,
  • Marcos Luciano Bruschi

DOI
https://doi.org/10.1590/1678-4324-2024230951
Journal volume & issue
Vol. 67

Abstract

Read online Read online

Abstract Brazil is a large sheep and cow producer, and the development of new strategies for the treatment of lamb umbilical cord healing as well as the bovine mastitis is very important. The aim of this study was to develop emulgels containing propolis, curcumin and andiroba oil for the treatment of mastitis and umbilical cord healing in animals. The formulations were composed of poly (acrylic acid) derivative (Carbopol 974P or polycarbophil), Brazilian green propolis extract, curcumin, and andiroba oil. The systems were investigated as the activity on umbilical cord healing of newborn lambs, and evaluation of the prevention of mastitis in dairy cows. The emulgels effectively promoted umbilical cord healing, preventing infections. Moreover, they were effective for reducing the somatic cell count a health indicator for mammary glands in cows. These findings suggest that these formulations can potentially treat cattle mastitis and improve lambs' umbilical cord healing.

Keywords