Hydrofluoric Acid-Free Digestion of Organosilicon Nanoparticles for Bioanalysis by ICP-OES

Nooshin Yousefpour; Olof Björnberg; Ingrid Yao Mattisson; Oskar Axelsson

doi:10.3390/micro3010019

Micro (Mar 2023)

Hydrofluoric Acid-Free Digestion of Organosilicon Nanoparticles for Bioanalysis by ICP-OES

Nooshin Yousefpour,
Olof Björnberg,
Ingrid Yao Mattisson,
Oskar Axelsson

Affiliations

Nooshin Yousefpour: Spago Nanomedical AB, Scheelevägen 22, 223 63 Lund, Sweden
Olof Björnberg: Spago Nanomedical AB, Scheelevägen 22, 223 63 Lund, Sweden
Ingrid Yao Mattisson: Spago Nanomedical AB, Scheelevägen 22, 223 63 Lund, Sweden
Oskar Axelsson: Spago Nanomedical AB, Scheelevägen 22, 223 63 Lund, Sweden

DOI: https://doi.org/10.3390/micro3010019
Journal volume & issue: Vol. 3, no. 1
pp. 264 – 273

Abstract

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A novel ICP-OES method has been developed for the determination of Si concentration, originating from polyorganophosphosilanes, in biological specimens that also contain metal ions. The method is free of hazardous hydrofluoric acid (HF) and involves digestion with HNO3/H2O2 prior to the analysis by ICP-OES. High and reproducible spike recovery was obtained from the controls.

Published in Micro

ISSN: 2673-8023 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Physics; Science: Natural history (General): Microscopy; Science: Microbiology; Science: Chemistry
Website: https://www.mdpi.com/journal/micro

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