Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition

• Laura Ordovás,
• Ruben Boon,
• Mariaelena Pistoni,
• Yemiao Chen,
• Esther Wolfs,
• Wenting Guo,
• Rangarajan Sambathkumar,
• Sylwia Bobis-Wozowicz,
• Nicky Helsen,
• Jolien Vanhove,
• Pieter Berckmans,
• Qing Cai,
• Kim Vanuytsel,
• Kristel Eggermont,
• Veerle Vanslembrouck,
• Béla Z. Schmidt,
• Susanna Raitano,
• Ludo Van Den Bosch,
• Yaakov Nahmias,
• Toni Cathomen,
• Tom Struys,
• Catherine M. Verfaillie

Affiliations

Laura Ordovás

Corresponding author

Ruben Boon

Mariaelena Pistoni

Yemiao Chen

Esther Wolfs

Wenting Guo

Rangarajan Sambathkumar

Sylwia Bobis-Wozowicz

Nicky Helsen

Jolien Vanhove

Pieter Berckmans

Qing Cai

Kim Vanuytsel

Kristel Eggermont

Veerle Vanslembrouck

Béla Z. Schmidt

Susanna Raitano

Ludo Van Den Bosch

Yaakov Nahmias

Toni Cathomen

Tom Struys

Catherine M. Verfaillie

Corresponding author