Nature Communications (Jun 2021)
Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes
Abstract
Bioorthogonal diversification of peptides is generally dependent on impractical prefunctionalization methods. Here, the authors develop a manganese(I)-catalyzed C–H fluorescent labeling with BODIPY probes, which enables the development of activatable fluorophores to image cell function.