Elimination of HIV-1 genomes from human T-lymphoid cells by CRISPR/Cas9 gene editing

• K. Khalili,
• R. Kaminski,
• Y. Chen,
• T. Fischer,
• E. Tedaldi,
• A. Napoli,
• Y. Zhang,
• J. Karn,
• W. Hu

Affiliations

K. Khalili

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

R. Kaminski

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

Y. Chen

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

T. Fischer

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

E. Tedaldi

Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA; Department of Medicine, Temple HIV Program, Temple University School of Medicine, Philadelphia, PA 19140, USA

A. Napoli

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

Y. Zhang

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA

J. Karn

Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, OH 44106, USA

W. Hu

Department of Neuroscience/Center for Neurovirology, Temple University School of Medicine, Philadelphia, PA 19140, USA; Comprehensive NeuroAIDS Center, Temple University School of Medicine, Philadelphia, PA 19140, USA