Asian Journal of Surgery (Mar 2018)

Value of preoperative biliary drainage on postoperative outcome after pancreaticoduodenectomy: A case–control study

  • Ayman El Nakeeb,
  • Ali Salem,
  • Yousef Mahdy,
  • Mohamed El Dosoky,
  • Rami Said,
  • Mohamed Abd Ellatif,
  • Helmy Ezzat,
  • Ahmed M. Elsabbagh,
  • Hosam Hamed,
  • Talaat Abd Alah,
  • Gamal El Ebidy

DOI
https://doi.org/10.1016/j.asjsur.2016.10.004
Journal volume & issue
Vol. 41, no. 2
pp. 155 – 162

Abstract

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Background/Objective: The potential benefit of preoperative biliary drainage (PBD) on postoperative outcomes remains controversial. The aim of this study was to elucidate surgical outcomes of pancreaticoduodenectomy (PD) in patients with PBD and to show the impact of bilirubin level. Methods: We retrospectively studied all patients who underwent PD in our center between January 2003 and June 2015. Patients were divided into: Group A (PBD) and Group B (no PBD). The primary outcome was the rate of postoperative complication. Results: A total of 588 cases underwent PD. Group A included 314 (53.4%) patients while Group B included 274 (46.6%) patients. The overall incidence of complications and its severity were higher in Group A (p = 0.03 and p = 0.02). There was significant difference in the incidence of postoperative pancreatic fistula (p = 0.002), delayed gastric emptying (p = 0.005), biliary leakage (p = 0.04), abdominal collection (p = 0.04), and wound infection (p = 0.04) in Group A. The mean length of hospital stay was significantly longer in Group A than in Group B (12.86 ± 7.65 days vs. 11.05 ± 7.98 days, p = 0.01). No significant impact of preoperative bilirubin level on surgical outcome was detected. Conclusion: PBD before PD was associated with major postoperative complications and stent-related complications.

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