Acta Crystallographica Section E (Nov 2010)

N-(2-Chloropyrimidin-4-yl)-N,2-dimethyl-2H-indazol-6-amine

  • Hao-Fei Qi,
  • Bing-Ni Liu,
  • Mo Liu,
  • Deng-Ke Liu

DOI
https://doi.org/10.1107/S1600536810042753
Journal volume & issue
Vol. 66, no. 11
pp. o2955 – o2955

Abstract

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In the title compound, C13H12ClN5, which is a derivative of the antitumor agent pazopanib {systematic name: 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrimidine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of molecules related by twofold rotational symmetry are linked into dimers through π–π interactions between the indazole ring systems [centroid–centroid distance = 3.720 (2) Å]. Weak intermolecular C—H...N hydrogen bonds further assemble these dimers into columns propagated in [001].