Emerging Infectious Diseases (Apr 2008)

Single Nucleotide Polymorphism Typing of Bacillus anthracis from Sverdlovsk Tissue

  • Richard T. Okinaka,
  • Melinda Henrie,
  • Karen K. Hill,
  • KristinS. Lowery,
  • Matthew Van Ert,
  • Talima Pearson,
  • James Schupp,
  • Leo Kenefic,
  • Jodi Beaudry,
  • Steven A. Hofstadler,
  • Paul J. Jackson,
  • Paul Keim

DOI
https://doi.org/10.3201/eid1404.070984
Journal volume & issue
Vol. 14, no. 4
pp. 653 – 656

Abstract

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A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient’s B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.

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