Nature Communications (Mar 2020)

Encoding of contextual fear memory in hippocampal–amygdala circuit

  • Woong Bin Kim,
  • Jun-Hyeong Cho

DOI
https://doi.org/10.1038/s41467-020-15121-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 22

Abstract

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Previous studies implicate the hippocampal–amygdala pathway in contextual fear conditioning, in which animals learn to associate a neutral context with an aversive stimulus and display fear responses to dangerous situations. Here the authors show that selective strengthening of hippocampal–amygdala pathway contributes to encoding adaptive fear memory for threat-predictive context.