The Relationship between Abnormal Ankle-brachial Index and Micro-vascular Complications of Diabetes Type II

Abstract

Background:The prevalence of diabetes mellitus is increasing worldwide and the relationship between peripheral vascular involvement and the complications of diabetes disease, such as retinopathy, has been reported in some studies but has not yet been fully proven. The aim of this study was to investigate the relationship between diabetes complications and peripheral and central vascular involvement. Method:A number of 150 patients with diabetes type II aged 30 to 70 years old were entered into this cross- sectional study. Ankle-brachial index (ABI), carotid intima media thickness and diabetes complications were investigated in them. Results:Abnormal ABI was more prevalent (79%) in Female patients. Furthermore, diabetes disease duration (P=0.005), systolic blood pressure (P=0.005) and retinopathy (P=0.003) were higher in females. Based on regression model, the highest relation of abnormal ABI incidence was observed with female gender (OR=2.4). Moreover, only blood pressure was among the abnormal ABI effective risk factors. Conclusion:Female gender, duration of diabetes disease, systolic blood pressure and retinopathy incidence were among the effective factors in the incidence of abnormal ABI and abnormal ABI had a direct and reverse relationship with causing vascular diseases in diabetic type II patients.

Keywords

• diabetes mellitus ankle
• brachial index carotid intima media thickness diabetes complications