G3: Genes, Genomes, Genetics (Jan 2023)

A polygenic basis for birth weight in a wild population of red deer (<i>Cervus elaphus</i>)

  • Julie Gauzere,
  • Josephine M Pemberton,
  • Jon Slate,
  • Alison Morris,
  • Sean Morris,
  • Craig A Walling,
  • Susan E Johnston

DOI
https://doi.org/10.1093/g3journal/jkad018
Journal volume & issue
Vol. 13, no. 4

Abstract

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AbstractThe genetic architecture of traits under selection has important consequences for the response to selection and potentially for population viability. Early QTL mapping studies in wild populations have reported loci with large effect on trait variation. However, these results are contradicted by more recent genome-wide association analyses, which strongly support the idea that most quantitative traits have a polygenic basis. This study aims to re-evaluate the genetic architecture of a key morphological trait, birth weight, in a wild population of red deer (Cervus elaphus