Novel Dual Ligands Targeting Sigma1 Receptor and Acetylcholinesterase Endowed with Antioxidant Properties

Affiliations

Giacomo Rossino: Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 6 and 12, 27100 Pavia, Italy
Marta Rui: Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 6 and 12, 27100 Pavia, Italy
Dirk Schepmann: Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Correnstrasse 48, 48149 Muenster, Germany
Bernard Wünsch: Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Correnstrasse 48, 48149 Muenster, Germany
Stefania Monteleone: Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marbacher Weg 6, 35032 Marburg, Germany
Klaus Liedl: Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria
Vittorio Pace: Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
Daniela Rossi: Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 6 and 12, 27100 Pavia, Italy
Simona Collina: Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 6 and 12, 27100 Pavia, Italy

Abstract

Neurodegenerative disorders represent one of the main therapeutic challenges of our time. [...]