Antithyroid drug induced agranulocytosis: what still we need to learn ?

Abstract

Antithyroid drugs (ATDs) induced agranulocytosis is a rare but life threatening condition. We report a 29 years Filipino female diagnosed as having hyperthyroidism with normal base line blood counts, liver and renal profile. She was started on maximum 60mg (20mg TID) oral dose of carbimazole since one month by her treating physician. Exactly after one month of treatment she presented to emergency room (ER) with fever, sore throat and generalized weakness for several days.

Keywords

• hyperthyroidism
• atd-antithyroid drugs
• agranulocytosis
• granulocyte colony stimulating factor