Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis

Abstract

Background The coexistence of amyotrophic lateral sclerosis (ALS) with clinical forms of Parkinson disease (PD), although uncommon, is found to a greater degree than one would expect by chance. The pathological mechanisms of ALS and PD are still not fully understood, and the coexistence of these two diseases suggests that they could share mechanisms in common.

Keywords

• Amyotrophic Lateral Sclerosis
• Parkinson Disease
• Dopamine Plasma Membrane Transport Proteins
• Striatonigral Degeneration
• SPECT
• Esclerose Amiotrófica Lateral
• Doença de Parkinson
• Proteínas da Membrana Plasmática de Transporte de Dopamina
• Degeneração Estriatonigral
• SPECT