Nature Communications (Mar 2021)

Overcoming the design, build, test bottleneck for synthesis of nonrepetitive protein-RNA cassettes

  • Noa Katz,
  • Eitamar Tripto,
  • Naor Granik,
  • Sarah Goldberg,
  • Orna Atar,
  • Zohar Yakhini,
  • Yaron Orenstein,
  • Roee Amit

DOI
https://doi.org/10.1038/s41467-021-21578-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

Read online

Phage-coat proteins can be used to build synthetic biology parts. Here the authors use an oligo library and machine learning to predict and verify sequences based on binding scores.