Novel silver(I) compounds with 1-adamantanamine

Abstract

In this work, three novel silver(I) complexes with an almost completely rigid and bulky monodentate ligand, 1-adamantanamine, were synthesized. The aliphatic amine, 1-adamantanamine, is the sole electron donor ligand in these complexes. In addition to spectroscopic characterization, the basic biological activities of the new compounds were investigated and their minimum inhibitory concentrations were determined. The antifungal and antibacterial activities indicate that these compounds could potentially be applied as new therapeutics. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 172017, Grant no. 172035 and Grant no. III 43004]

Keywords

• amantadine
• silver(I) complexes
• rigid and bulky ligand
• NMR spectroscopy
• biological activity