Stem Cell Research (Aug 2020)

Generation of a human induced pluripotent stem cell line (SHUPLi001-A) from PBMCs of a healthy male donor

  • Yijun Cai,
  • Junyi Lin,
  • Kaijun Ma,
  • Meng He,
  • Beixu Li

Journal volume & issue
Vol. 47
p. 101871

Abstract

Read online

Human induced pluripotent stem cells (iPSCs) are an ideal model for pathomechanism investigation and drug screening due to their differentiation potency. Here, we generated an iPSC line, SHUPLi001-A, from peripheral blood mononuclear cells (PBMCs) of a healthy 30-year-old male individual using non-integrating Sendai virus. Characterization of SHUPLi001-A was confirmed by the expression of typical pluripotency markers and by the teratoma formation assay to assess differentiation potency in vivo.