Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Clarissa Mitri Espanhol; Júlia Kanaan Recuero; Danielle Machado Pagani; Amanda Carvalho Ribeiro; Gerson Vettorato; Rodrigo Pereira Duquia; Laura Luzzatto; Maria Lúcia Scroferneker

Medical Mycology Case Reports (Mar 2020)

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

Clarissa Mitri Espanhol,
Júlia Kanaan Recuero,
Danielle Machado Pagani,
Amanda Carvalho Ribeiro,
Gerson Vettorato,
Rodrigo Pereira Duquia,
Laura Luzzatto,
Maria Lúcia Scroferneker

Affiliations

Clarissa Mitri Espanhol: Department of Dermatology of the Hospital Santa Casa de Misericórdia de Porto Alegre, Rua Prof. Annes Dias, 285, Porto Alegre, CEP:90020-090, Brazil
Júlia Kanaan Recuero: Department of Dermatology of the Hospital Santa Casa de Misericórdia de Porto Alegre, Rua Prof. Annes Dias, 285, Porto Alegre, CEP:90020-090, Brazil
Danielle Machado Pagani: Postgraduate Program in Agricultural and Environmental Microbiology, Federal University of Rio Grande do Sul.Rua Sarmento Leite, 500, Sala 325, Porto Alegre, Rio Grande do Sul, CEP: 90050-170, Brazil
Amanda Carvalho Ribeiro: Faculty of Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Avenida Ipiranga, 2752, CEP: 90610-000, Brazil
Gerson Vettorato: Department of Dermatology of the Hospital Santa Casa de Misericórdia de Porto Alegre, Rua Prof. Annes Dias, 285, Porto Alegre, CEP:90020-090, Brazil
Rodrigo Pereira Duquia: Department of Dermatology of the Hospital Santa Casa de Misericórdia de Porto Alegre, Rua Prof. Annes Dias, 285, Porto Alegre, CEP:90020-090, Brazil
Laura Luzzatto: Department of Microbiology, ICBS, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite, 500, Sala 325, Porto Alegre, Rio Grande do Sul, CEP: 90050-170, Brazil
Maria Lúcia Scroferneker: Department of Microbiology, ICBS, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite, 500, Sala 325, Porto Alegre, Rio Grande do Sul, CEP: 90050-170, Brazil; Corresponding author. Department of Microbiology, ICBS, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite, 500, Room, 325, Porto Alegre, CEP: 90050-170, Brazil.

Journal volume & issue: Vol. 27
pp. 39 – 41

Abstract

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We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients. Keywords: Exophiala xenobiotica, Phaeohyphomycosis, Immunosuppressed, Renal transplantation

Published in Medical Mycology Case Reports

ISSN: 2211-7539 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General); Science: Biology (General)
Website: https://www.journals.elsevier.com/medical-mycology-case-reports/

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