Australasian Orthodontic Journal (May 2014)

Denervation and β2-adrenoceptor-agonist administration on craniofacial bone density

  • Fitzpatrick Brendan,
  • Woods Michael,
  • Lynch Gordon,
  • Manton David

DOI
https://doi.org/10.2478/aoj-2014-0004
Journal volume & issue
Vol. 30, no. 1
pp. 32 – 38

Abstract

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Objective: β2-agonist medications are thought to have adverse effects on bone density. Surgical denervation and intramuscular β2-agonist injections appear to have opposing effects on skeletal muscles. The present study has been designed to assess the effects of denervation of the masseter, intramuscular injection of a β2-agonist and the combination of both procedures, on bone density in the craniofacial skeleton in rats.