Features of structure of external layer of murine hair at different stages of malignant tumor development

Abstract

In the paper, the results of experimental investigations on the differences of wool structure of healthy mice and mice with malignant tumor(s) are represented. It is shown that destruction of wool structure happens during pathology development. Quantity of cells of external wool layer and their thickness decrease when the tumor capsule enlarges. Difference is seen even when the tumor is small. The obtained results can be used to improve optical techniques of biomedical diagnostics of cancer diseases.

Keywords

• Breast cancer
• hair
• optical biomedical diagnostics
• atomic force microscopy
• dynamic light scattering