Gynecologic Oncology Reports (Aug 2018)
Everolimus and papillomavirus lesions in female renal transplant recipient: A case report
Abstract
We describe the case of a transplanted patient with high-risk HPV infection that manifested as multiple genital condylomas and abnormal Papanicolaou (Pap) smear. Her immunosuppressants were corticosteroids, cyclosporine, and azathioprine. Since gynecologic treatments to eradicate condylomas were completely unsuccessful, cyclosporine was replaced by everolimus. Soon after, condylomas disappeared, HPV status became negative, and Pap smear returned to normal and has remained normal since. Keywords: Human papillomavirus, Everolimus, Genital condyloma, Renal transplantation, Cervical intraepithelial neoplasia