Novel Thiourea Ligands—Synthesis, Characterization and Preliminary Study on Their Coordination Abilities

Abstract

Two series of polydentate N,O,S-ligands containing thiourea fragments attached to a p-cresol scaffold, unsymmetrical mono-acylated bis-amines and symmetrical bis-thioureas, are obtained by common experiments. It is observed that the reaction output is strongly dependent on both bis-amine and thiocarbamic chloride substituents. The products are characterized by 1D and 2D NMR spectra in solution and by single crystal XRD. A preliminary study on the coordination abilities of selected products is performed by ITC at around neutral media.

Keywords

• polydentate ligands
• unsymmetrical and symmetrical thioureas
• NMR
• XRD
• ITC