Nature Communications (Jul 2022)

Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales

  • Abigail Kalmbach,
  • Vanessa Winiger,
  • Nuri Jeong,
  • Arun Asok,
  • Charles R. Gallistel,
  • Peter D. Balsam,
  • Eleanor H. Simpson

DOI
https://doi.org/10.1038/s41467-022-31377-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Dopamine in the ventral striatum conveys a complex reward-associated signal. This study demonstrates how dopamine reflects sustained reward availability, and rapidly signals unexpected changes in availability.