Vitiligo: Etiological Study

Abstract

Vitiligo is an acquired pigmentary disorder of the skin that is characterized by circumscribed, depigmented macules and patches. Has an estimated prevalence of 0.5–2% of the population worldwide The condition is frequently associated with disorders of autoimmune origin and hereditary susceptibility in vitiligo patients may refer to proteins that are shown by melanin cells that are autoantigens that target melanin cells to destroy by the immune system. This review summarizes the current knowledge on vitiligo and attempts to give an overview of biochemical, immunogenic and genes that responsible or that may be candidates for the events of the Vitiligo disease.