Development of Complex Genotyping Algorithm and Methods of Evaluation of the Genetic Diversity of Plague and Cholera Agents Natural Strains

Abstract

Present review summarizes the literary data on applying the modern molecular genetic methods to analyze the diversity of natural strains of plague and cholera agents. Chosen was the complex of most perspective methods on the basis of which was developed the algorithm of gene-diagnostic analysis of Yersinia pestis and Vibrio cholerae strains.

Keywords

• plague and cholera agents
• genetic diversity
• genotyping algorithm