Comparative Analysis of the State of Hepatobiliary System in Children Who Live in the Regions Polluted with Different Types of Xenobiotics

Abstract

It has been carried out a comparative analysis of sonographic and biochemical parameters of the hepatobiliary system state in 63 children living in environmentally unfriendly regions with different route of xenoiotic enter to the body in order to optimize early diagnosis of environmental hepatobiliary disease. It has been found that environmental disease in examined children was of multisystem nature, the leading nosologies of which were hepatobiliary, renal and thyroid pathologies. It was found that in children with xenobiotics, intaked with the food, disorders had more severe clinical course and besides the biochemical signs of cholestasis we detected slight increase of hepatocellular enzymes unlike the children with inhalation way of xenobiotics exposure, and early laboratory signs of cholestasis syndrome only occurred.

Keywords

• hepatobiliary pathology
• children
• environmental disease