Fluorescein-aided resection of fusiform gyrus neurocysticercosis in a patient with medically refractory epilepsy localized to the anterior hippocampus: Case report and surgical technique

Abstract

Background: Neurocysticercosis is the leading cause of epilepsy worldwide. It occasionally requires neurosurgical intervention, but intraoperative localization can be challenging. Sodium fluorescein has yet to be explored in many non-neoplastic processes. Case Presentation: A patient with medically refractory epilepsy was found to have a right temporal lesion consistent with neurocysticercosis. Seizure foci were localized to the ipsilateral hippocampus, prompting RNS implantation and lesion resection. The cysticercal lesion avidly fluoresced after intraoperative administration of sodium fluorescein, which promoted total resection. Conclusion: This surgical case report describes the investigational use of sodium fluorescein for localization and resection of a non-neoplastic lesion in a safer and more precise manner. Further investigation could prompt wider clinical use.

Keywords

• Seizure
• Neurocysticercosis
• Parasite
• Sodium fluorescein
• Epilepsy
• Neurosurgery