IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME

Abstract

The results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia; reduction in the relative and absolute T-lymphocyte numbers, and of subpopulations of CD4 lymphocytes, as well as levels of phagocytosis. The data presented indicates that inclusion of immunomodulators into the treatment program in patients with pyo-necrotic forms of diabetic foot led to a reduction in treatment time, complications, and to positive changes in the parameters characterizing the state of the immune system.

Keywords

• сахарный диабет
• синдром диабетической стопы
• диабетическая гангрена
• иммунитет
• вторичная иммунная недостаточность
• иммунокоррекция
• синдром системной воспалительной реакции
• лечение
• diabetes mellitus
• diabetic foot syndrome
• diabetic gangrene
• immunity
• secondary immunodeficiency
• immunocorrection
• systemic inflammatory response syndrome
• treatment