Haematologica (Aug 2012)

Development and validation of a predictive model for death in acquired severe ADAMTS13 deficiency-associated idiopathic thrombotic thrombocytopenic purpura: the French TMA Reference Center experience

  • Ygal Benhamou,
  • Cyrielle Assié,
  • Pierre-Yves Boelle,
  • Marc Buffet,
  • Rana Grillberger,
  • Sandrine Malot,
  • Alain Wynckel,
  • Claire Presne,
  • Gabriel Choukroun,
  • Pascale Poullin,
  • François Provôt,
  • Didier Gruson,
  • Mohamed Hamidou,
  • Dominique Bordessoule,
  • Jacques Pourrat,
  • Jean-Paul Mira,
  • Véronique Le Guern,
  • Claire Pouteil-Noble,
  • Cédric Daubin,
  • Philippe Vanhille,
  • Eric Rondeau,
  • Jean-Bernard Palcoux,
  • Christiane Mousson,
  • Cécile Vigneau,
  • Guy Bonmarchand,
  • Bertrand Guidet,
  • Lionel Galicier,
  • Elie Azoulay,
  • Hanspeter Rottensteiner,
  • Agnès Veyradier,
  • Paul Coppo

DOI
https://doi.org/10.3324/haematol.2011.049676
Journal volume & issue
Vol. 97, no. 8

Abstract

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Background Acquired thrombotic thrombocytopenic purpura is still associated with a 10–20% death rate. It has still not been possible to clearly identify early prognostic factors of death. This study involved thrombotic thrombocytopenic purpura patients with acquired severe (