Pneumocystis jirovecii Pneumonia in an Immunocompetent Japanese Man: A Case Report and Literature Review

Hiromi Ide; Yoshikazu Yamaji; Kazunori Tobino; Masanobu Okahisa; Kojin Murakami; Yuki Goto; Takuto Sueyasu; Saori Nishizawa; Kohei Yoshimine; Miyuki Munechika; Masafumi Oya; Yuka Hiraki

doi:10.1155/2019/3981681

Case Reports in Pulmonology (Jan 2019)

Pneumocystis jirovecii Pneumonia in an Immunocompetent Japanese Man: A Case Report and Literature Review

Hiromi Ide,
Yoshikazu Yamaji,
Kazunori Tobino,
Masanobu Okahisa,
Kojin Murakami,
Yuki Goto,
Takuto Sueyasu,
Saori Nishizawa,
Kohei Yoshimine,
Miyuki Munechika,
Masafumi Oya,
Yuka Hiraki

Affiliations

Hiromi Ide: Department of Respiratory Medicine, Iizuka Hospital, Japan
Yoshikazu Yamaji: Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Japan
Kazunori Tobino: Department of Respiratory Medicine, Iizuka Hospital, Japan
Masanobu Okahisa: Department of Respiratory Medicine, Iizuka Hospital, Japan
Kojin Murakami: Department of Respiratory Medicine, Iizuka Hospital, Japan
Yuki Goto: Department of Respiratory Medicine, Iizuka Hospital, Japan
Takuto Sueyasu: Department of Respiratory Medicine, Iizuka Hospital, Japan
Saori Nishizawa: Department of Respiratory Medicine, Iizuka Hospital, Japan
Kohei Yoshimine: Department of Respiratory Medicine, Iizuka Hospital, Japan
Miyuki Munechika: Department of Respiratory Medicine, Iizuka Hospital, Japan
Masafumi Oya: Department of Pathology, Iizuka Hospital, Japan
Yuka Hiraki: Department of Pathology, Iizuka Hospital, Japan

DOI: https://doi.org/10.1155/2019/3981681
Journal volume & issue: Vol. 2019

Abstract

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We herein report the case of a 37-year-old immunocompetent man who died from Pneumocystis jirovecii pneumonia (PCP). He was initially treated for an acute exacerbation of interstitial pneumonia; however, the elevation of the patient’s serum (1-3) β-D glucan (BG) level suggested the possibility of PCP and sulfamethoxazole trimethoprim was added. A postmortem pathological examination and retrospective Grocott's methenamine silver (GMS) staining of the bronchoalveolar lavage fluid (BALF), which was obtained on the day of admission, revealed PCP. The present case suggests that it is essential to perform a BG assay and GMS staining of BALF specimens when patients show diffuse ground-glass opacity on chest computed tomography, regardless of their immune status.

Published in Case Reports in Pulmonology

ISSN: 2090-6846 (Print); 2090-6854 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://onlinelibrary.wiley.com/journal/9796

About the journal