Case Reports in Neurological Medicine (Jan 2015)

GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure

  • Matthew C. Loftspring,
  • Eric Landsness,
  • Lindsey Wooliscroft,
  • Robert Rudock,
  • Sally Jo,
  • Kevin R. Patel

DOI
https://doi.org/10.1155/2015/812035
Journal volume & issue
Vol. 2015

Abstract

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Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.