Canadian Journal of Gastroenterology (Jan 2013)

The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy

  • Sherif El-Saadany,
  • Dina H Ziada,
  • Hanan El Bassat,
  • Wael Farrag,
  • Hesham El-Serogy,
  • Manal Eid,
  • Manal Abdallah,
  • Medhat Ghazy,
  • Hoda A Salem

DOI
https://doi.org/10.1155/2013/562765
Journal volume & issue
Vol. 27, no. 2
pp. e13 – e17

Abstract

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BACKGROUND: The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.