Echinacea purpurea extract (cichoric acid) exerts an anti-inflammatory effect on yak PBMCs and regulates the TLR4 signalling pathway

Xue Cai-hua; A Shun-xian; Wang Meng-jie; Wu Qiang; Liu Jia-hua; Zhang Long-fei; Wu Yun; Wu Hua; Chai Sha-tuo

doi:10.2478/jvetres-2021-0016

Journal of Veterinary Research (Mar 2021)

Echinacea purpurea extract (cichoric acid) exerts an anti-inflammatory effect on yak PBMCs and regulates the TLR4 signalling pathway

Xue Cai-hua,
A Shun-xian,
Wang Meng-jie,
Wu Qiang,
Liu Jia-hua,
Zhang Long-fei,
Wu Yun,
Wu Hua,
Chai Sha-tuo

Affiliations

Xue Cai-hua: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
A Shun-xian: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
Wang Meng-jie: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
Wu Qiang: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
Liu Jia-hua: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
Zhang Long-fei: College of Agriculture and Animal Husbandry, Qinghai University, XiningQinghai Province810016, People’s Republic of China
Wu Yun: College of Agronomy and Biotechnology, Zun Normal College, Zunyi, Guizhou Province563006, People’s Republic of China
Wu Hua: State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai Province810016, People’s Republic of China
Chai Sha-tuo: College of Animal Science and Veterinary Medicine, Qinghai University, XiningQinghai Province810016, People’s Republic of China

DOI: https://doi.org/10.2478/jvetres-2021-0016
Journal volume & issue: Vol. 65, no. 1
pp. 109 – 115

Abstract

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Inflammation is one of the main causes of impaired health in livestock and some of its processes weaken animal productivity and impact human health. The present study was conducted to evaluate the effect of echinacea extract (cichoric acid – CA) on yak peripheral blood mononuclear cells (PBMCs), inflammatory-related factors, and the toll-like receptor (TLR)4 signalling pathway induced by lipopolysaccharide (LPS) in these PBMCs.

Published in Journal of Veterinary Research

ISSN: 2450-8608 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Agriculture: Animal culture: Veterinary medicine
Website: https://sciendo.com/journal/JVETRES

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