Site-selective electrooxidation of methylarenes to aromatic acetals

Peng Xiong; Huai-Bo Zhao; Xue-Ting Fan; Liang-Hua Jie; Hao Long; Pin Xu; Zhan-Jiang Liu; Zheng-Jian Wu; Jun Cheng; Hai-Chao Xu

doi:10.1038/s41467-020-16519-8

Nature Communications (Jun 2020)

Site-selective electrooxidation of methylarenes to aromatic acetals

Peng Xiong,
Huai-Bo Zhao,
Xue-Ting Fan,
Liang-Hua Jie,
Hao Long,
Pin Xu,
Zhan-Jiang Liu,
Zheng-Jian Wu,
Jun Cheng,
Hai-Chao Xu

Affiliations

Peng Xiong: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Huai-Bo Zhao: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Xue-Ting Fan: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Liang-Hua Jie: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Hao Long: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Pin Xu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Zhan-Jiang Liu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Zheng-Jian Wu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Jun Cheng: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University
Hai-Chao Xu: State Key Laboratory of Physical Chemistry of Solid Surfaces, Innovative Collaboration Center of Chemistry for Energy Materials, and College of Chemistry and Chemical Engineering, Xiamen University

DOI: https://doi.org/10.1038/s41467-020-16519-8
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 8

Abstract

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Benzylic oxygenation of methylarenes is a direct but challenging method for aldehyde synthesis from simple starting materials. Here, the authors show an electrochemical, site-selective method for the oxidation of methyl benzoheterocycles to aromatic acetals without using chemical oxidants or transition metal catalysts.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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