Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

• Sebastiaan T. A. Koenders,
• Lukas S. Wijaya,
• Martje N. Erkelens,
• Alexander T. Bakker,
• Vera E. van der Noord,
• Eva J. van Rooden,
• Lindsey Burggraaff,
• Pasquale C. Putter,
• Else Botter,
• Kim Wals,
• Hans van den Elst,
• Hans den Dulk,
• Bogdan I. Florea,
• Bob van de Water,
• Gerard J. P. van Westen,
• Reina E. Mebius,
• Herman S. Overkleeft,
• Sylvia E. Le Dévédec,
• Mario van der Stelt

Affiliations

Sebastiaan T. A. Koenders

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Lukas S. Wijaya

Cancer Therapeutics and Drug Safety, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Martje N. Erkelens

Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Centra, Amsterdam, The Netherlands

Alexander T. Bakker

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Vera E. van der Noord

Cancer Therapeutics and Drug Safety, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Eva J. van Rooden

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Lindsey Burggraaff

Computational Drug Discovery, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Pasquale C. Putter

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Else Botter

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Kim Wals

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Hans van den Elst

Department of Bio-Organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Hans den Dulk

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Bogdan I. Florea

Department of Bio-Organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Bob van de Water

Cancer Therapeutics and Drug Safety, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Gerard J. P. van Westen

Computational Drug Discovery, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Reina E. Mebius

Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Centra, Amsterdam, The Netherlands

Herman S. Overkleeft

Department of Bio-Organic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Sylvia E. Le Dévédec

Cancer Therapeutics and Drug Safety, Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands

Mario van der Stelt

Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands