Keep cool! Observed temperature variations at different process stages of the biobanking workflow – examples from the Leipzig medical biobank

Abstract

Biobanked samples are becoming increasingly important for research outcomes. Most of the biobanking processes (from preparation to storage) are affected by temperature in a time-dependent manner and have a high impact on sample quality. We aimed to validate time and temperature sensitive processes such as sample preparation, transport, sorting, and storage, which have a high impact on sample quality.

Keywords

• biobanking
• cryopreservation
• pre-analytical validation
• storage temperature
• ultra-low temperature freezers