Haematologica (May 2007)

Accuracy of leukocyte alkaline phosphatase score to predict JAK2 V617F mutation

  • Ana L Basquiera,
  • Fernanda Fassetta,
  • Néstor Soria,
  • José Moreno Barral,
  • Brenda Ricchi,
  • Juan J García

DOI
https://doi.org/10.3324/haematol.10991
Journal volume & issue
Vol. 92, no. 5

Abstract

Read online

Granulocyte activation parameters have been described in patients with myeloproliferative disorders (MPD). We have evaluated the accuracy of leukocyte alkaline phosphatase (LAP) score to predict JAK2 V617F mutation. LAP score was obtained using a cytochemical reaction in granulocytes of patients’ peripheral blood with MPD.