Nature Communications (Apr 2016)
The Gonium pectorale genome demonstrates co-option of cell cycle regulation during the evolution of multicellularity
- Erik R. Hanschen,
- Tara N. Marriage,
- Patrick J. Ferris,
- Takashi Hamaji,
- Atsushi Toyoda,
- Asao Fujiyama,
- Rafik Neme,
- Hideki Noguchi,
- Yohei Minakuchi,
- Masahiro Suzuki,
- Hiroko Kawai-Toyooka,
- David R. Smith,
- Halle Sparks,
- Jaden Anderson,
- Robert Bakarić,
- Victor Luria,
- Amir Karger,
- Marc W. Kirschner,
- Pierre M. Durand,
- Richard E. Michod,
- Hisayoshi Nozaki,
- Bradley J. S. C. Olson
Affiliations
- Erik R. Hanschen
- Department of Ecology and Evolutionary Biology, University of Arizona
- Tara N. Marriage
- Division of Biology, Kansas State University
- Patrick J. Ferris
- Department of Ecology and Evolutionary Biology, University of Arizona
- Takashi Hamaji
- Donald Danforth Plant Science Center
- Atsushi Toyoda
- Center for Advanced Genomics, National Institute of Genetics
- Asao Fujiyama
- Center for Advanced Genomics, National Institute of Genetics
- Rafik Neme
- Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Biology
- Hideki Noguchi
- Center for Advanced Genomics, National Institute of Genetics
- Yohei Minakuchi
- Center for Information Biology, National Institute of Genetics
- Masahiro Suzuki
- Department of Biological Sciences, Graduate School of Science, University of Tokyo
- Hiroko Kawai-Toyooka
- Department of Biological Sciences, Graduate School of Science, University of Tokyo
- David R. Smith
- Department of Biology, Western University
- Halle Sparks
- Division of Biology, Kansas State University
- Jaden Anderson
- Division of Biology, Kansas State University
- Robert Bakarić
- Division of Molecular Biology, Ruđer Bošković Institute
- Victor Luria
- Department of Systems Biology, Harvard Medical School
- Amir Karger
- Research Computing Division, Harvard Medical School
- Marc W. Kirschner
- Department of Systems Biology, Harvard Medical School
- Pierre M. Durand
- Department of Ecology and Evolutionary Biology, University of Arizona
- Richard E. Michod
- Department of Ecology and Evolutionary Biology, University of Arizona
- Hisayoshi Nozaki
- Department of Biological Sciences, Graduate School of Science, University of Tokyo
- Bradley J. S. C. Olson
- Division of Biology, Kansas State University
- DOI
- https://doi.org/10.1038/ncomms11370
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 10
Abstract
The undifferentiated Gonium pectorale represents the initial transition to multicellularity. Here, Bradley Olson, Erik Hanschen and colleagues describe the genome of Gonium pectorale, demonstrating that co-option of the retinoblastoma cell cycle regulatory pathway was a key genetic change in the evolution of multicellularity.
