Blood Cell Counts and Blood Cell Ratios as Non-Specific Major Depressive Disorder Biomarkers

Abstract

Introduction: With an increasing prevalence of major depressive disorder (MDD) in population there is a particular interest in finding a suitable biomarker for diagnosis and prognosis of the disease. Many studies have shown that MDD is linked to a systemic inflammatory process, so blood elements counts and ratios have been suggested to be promising indicators in the management and effectiveness of the disease therapy. The aim of this retrospective study was to compare absolute and relative white blood cells counts and to search for any changes in their ratios before and after the therapy of the patients.

Keywords

• major depressive disorder (mdd)
• blood cell counts
• blood cell ratios
• biomarkers
• antidepressants
• venlafaxine