Nature Communications (Oct 2022)

Hospitalisation and mortality risk of SARS-COV-2 variant omicron sub-lineage BA.2 compared to BA.1 in England

  • H. H. Webster,
  • T. Nyberg,
  • M. A. Sinnathamby,
  • N. Abdul Aziz,
  • N. Ferguson,
  • G. Seghezzo,
  • P. B. Blomquist,
  • J. Bridgen,
  • M. Chand,
  • N. Groves,
  • R. Myers,
  • R. Hope,
  • E. Ashano,
  • J. Lopez-Bernal,
  • D. De Angelis,
  • G. Dabrera,
  • A. M. Presanis,
  • S. Thelwall

DOI
https://doi.org/10.1038/s41467-022-33740-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 6

Abstract

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In this cohort study, the authors investigate the risk of severe outcomes following infection from Omicron BA.1 and BA.2 sub-lineages. Using whole genome sequencing and electronic health record data for ~980,000 BA.1 and ~250,000 BA.2 cases in England, they find a slightly lower risk of death and hospitalisation associated with BA.2.