Therapeutic Advances in Neurological Disorders (Sep 2020)

The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective

  • Raed Alroughani,
  • Bart Van Wijmeersch,
  • Jabber Al Khaboori,
  • Isa Ahmed Alsharoqi,
  • Samar F. Ahmed,
  • Ali Hassan,
  • Jihad Inshasi,
  • Derk W. Krieger,
  • Mustafa Shakra,
  • Ahmed Osman Shatila,
  • Miklos Szolics,
  • Mohamed Khallaf,
  • Aly Ezzat

DOI
https://doi.org/10.1177/1756286420954119
Journal volume & issue
Vol. 13

Abstract

Read online

Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of relapsing-remitting multiple sclerosis (RRMS). However, the gaps in optimal care for this complex disease remain. Alemtuzumab (Lemtrada®) is a highly efficacious DMT that shows better patient outcomes and therapeutic benefits, but its use is under-recognized in the Gulf region. Experts in the care of multiple sclerosis shared their opinions based on study data and daily clinical experience in identifying the appropriate patient profile suitable for alemtuzumab’s therapeutic benefits. Age, disease activity and severity, disability status, physician experience, and economic condition are some of the key indicators for alemtuzumab use.