Fixed dose combinations for the treatment arterial hypertension: the real way to improve control

Abstract

Insufficient control of blood pressure levels of the essential hypertension in Russia (less than 30% for women, less than 20% for men) was proven by epidemiology trials. This article is a review of the present opportunities to increase efficacy of treating hypertension by application of combined anti-hypertensive therapy and the advantages of fixed dose combinations (FDC). The authors scientifically prove the importance of using the combination, including angiotensin I-converting enzyme perindopril arginine and the long-half time dihydropyridine calcium channel blocker amlodipine in various clinical cases. Also the article summarizes the research of real clinical practice proving the high efficiency and safety of perindopril arginine /amlodipine FDC.

Keywords

• arterial hypertension
• antihypertensive treatment
• pharmacological treatment
• combination treatment
• fixed dose combinations
• angio- tensin i-converting enzyme
• calcium channel blockers
• perindopril arginine
• amlodipine
• research of real clinical practice